The Department of Cellular & Physiological Sciences at the University of British Columbia invites applications for a Research Associate and/or Postdoctoral Research Fellow in the field of Pancreatic Cancer. Our research group is dedicated to improving our understanding of disease mechanisms from the cellular level up to the integrated systems physiology level. The group has recently obtained pilot funding to expand ongoing studies on the role of hyperinsulinemia and insulin signalling in pancreatic cancer, as well as links between pancreatic cancer and diabetes.

The Laboratory for Molecular Signalling is looking for extremely motivated post-doctoral fellows or research associates to join a dynamic, well-funded laboratory. We are part of the Diabetes Research Group (http://www.diabetes.ubc.ca/JJpage.htm), located at the Life Sciences Institute (http://www.lsi.ubc.ca/), at the University of British Columbia (www.ubc.ca) in Vancouver, Canada. Our laboratory studies many aspects of pancreatic cell fate and function. We employ a range of experimental approaches from single-cell imaging, to molecular biology, to in vivo studies on genetically engineered mice. Of particular interest are the mechanisms of insulin signalling. The laboratory is fully equipped for molecular biology, in vivo mouse studies, and a wide variety of single-cell imaging/physiology modalities (3D multi-channel imaging with deconvolution; FRET; FLIM-FRET; TIRFM; microinjection, flash photolysis). We also have access to numerous Core facilities within the Life Sciences Institute including FACS, and high-throughput/high-content imaging for screening. The Life Sciences Institute is also home to the UBC Centre for Disease modeling where in rodent studies can be conducted to understand the progression of pancreatic cancer in vivo. The laboratory is located within an extremely collaborative group and the potential for working together with other research teams is high.

Ideal applicants should possess strong CVs with multiple publications in fields related to pancreatic cancer, diabetes and/or signal transduction and show the potential for obtaining external salary support. Please also provide a detailed cover letter clearly stating your career goals and the types of studies you see yourself performing in our laboratory. Address the cover letter, with your CV, and contact information for three references to: Dr. James D. Johnson, Ph.D. james.d.johnson@ubc.ca), no later than November 30, 2009.

Salary will be commensurate with qualifications and experience. UBC hires on the basis of merit and is committed to employment equity. We encourage all qualified persons to apply; however, Canadians and permanent residents of Canada will be given priority.